| 1980 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 02/27 | South Carolina 14, Baptist 2 | B.Landrum (W, 1-0) | | Charleston, SC | | J.Curl (1) |
| 02/29 | South Carolina 15, Tennessee 0 | B.Baynham (W, 1-0) | | Columbia, SC | | R.Carraway, M.Boatwright |
| 03/06 | South Carolina 30, Wofford 0 | B.Landrum (W, 2-0) | | Columbia, SC | | J.Curl 2 (3), R.Lowery 2 (2), J.McCarthy (1), G.Jonson (1) |
| 03/10 | South Carolina 7, Furman 2 | B.Landrum (W, 3-0) | | Greenville, SC | | |
| 03/11 | South Carolina 12, Furman 3 | B.Baynham (W, 2-0) | | Greenville, SC | | E.Farquharson, T.Williams, P.Hollins |
| 03/14 | South Carolina 7, East Carolina 2 | D.Lubert (W, 1-0) | | Columbia, SC | | E.Farquharson, J.Curl, M.Boatwright, P.Hollins |
| 03/15 | South Carolina 12, Western Carolina 2 | M.Calvert (W, 1-0) | | Columbia, SC | | J.Curl |
| 03/16 | South Carolina 3, Maryland 1 | B.Landrum (W, 4-0) | | Columbia, SC | | |
| 03/17 | South Carolina 7, North Carolina 2 | J.Kucharski (W, 1-0) | | Chapel Hill, NC | | |
| 03/18 | South Carolina 11, Baptist 4 | B.Kish (W, 1-0) | | Columbia, SC | | P.Hollins, R.Carraway |
| 03/19 | South Carolina 9, Charlotte 0 | D.Lubert (W, 2-0) | | Columbia, SC | | P.Hollins |
| 03/21 | South Carolina 7, Ohio 5 | B.Landrum (W, 5-0) | M.Small (7) | Columbia, SC | | J.Curl |
| 03/22 | #7 South Carolina 4, Ohio 3 | B.Kish (W, 2-0) | | Columbia, SC | | |
| 03/25 | Georgia Southern 5, South Carolina 2 | | | Statesboro, GA | | |
| 03/25 | Georgia Southern 4, South Carolina 3 | | | Statesboro, GA | | |
| 03/26 | South Carolina 8, Francis Marion 3 | | | Florence, SC | | |
| 03/29 | South Carolina 1, Ohio State 0 | B.Landrum (W, 6-1) | | Columbia, SC | | |
| 03/29 | South Carolina 9, Ohio State 3 | J.Kucharski (W, 2-0) | | Columbia, SC | | R.Vollmer |
| 03/31 | South Carolina 10, Baptist 0 | D.Lubert (W) | | Charleston, SC | | |
| 04/02 | #1 Miami (Fla.) 9, #3 South Carolina 0 | B.Landrum (L, 6-2) | | Coral Gables, FL | | |
| 04/03 | Miami (Fla.) 5, South Carolina 0 | B.Baynham (L, 2-1) | | Coral Gables, FL | | |
| 04/04 | #3 South Carolina 15, #1 Miami (Fla.) 5 | M.Small (W, 1-0) | | Coral Gables, FL | | J.McCarthy |
| 04/05 | #3 South Carolina 8, #1 Miami (Fla.) 1 | D.Lubert (W) | | Coral Gables, FL | | J.McCarthy |
| 04/07 | South Carolina 8, North Carolina 5 | B.Landrum (W, 7-2) | | Columbia, SC | | E.Farquharson |
| 04/10 | Winthrop 2, South Carolina 1 | B.Baynham (L, 2-2) | | Columbia, SC | | J.Curl |
| 04/10 | South Carolina 8, Furman 0 | D.Lubert (W, 5-0) | | Columbia, SC | | J.McCarthy, R.Carraway |
| 04/11 | South Carolina 4, Mercer 1 | M.Calvert (W, 2-0) | | Columbia, SC | | |
| 04/12 | Mercer 5, South Carolina 3 | D.Gordon (L, 0-1) | | Columbia, SC | | |
| 04/15 | Clemson 9, South Carolina 3 | B.Kish (L, 3-2) | | Clemson, SC | | |
| 04/16 | Clemson 4, South Carolina 3 | D.Lubert (L, 5-1) | | Clemson, SC | | |
| 04/17 | South Carolina 5, Citadel 2 | M.Calvert (W, 3-0) | | Columbia, SC | | |
| 04/18 | South Carolina 6, Furman 3 | J.Kucharski (W, 3-0) | | Columbia, SC | | J.Curl |
| 04/19 | #2 South Carolina 14, Wofford 0 | R.Bledsoe (W, 1-0) | | Spartanburg, SC | | |
| 04/20 | South Carolina 13, Western Carolina 10 | M.Small (W, 2-0) | | Cullowhee, NC | | P.Hollins |
| 04/21 | South Carolina 8, Pfeiffer 4 | | | Columbia, SC | | |
| 04/23 | #6 South Carolina 22, UNC-Wilmington 2 | M.Calvert (W) | | Wilmington, NC | | K.Taylor |
| 04/24 | South Carolina 8, Baptist 2 | R.Bledsoe (W, 2-0) | | Columbia, SC | | E.Farquharson, J.Curl |
| 04/25 | #6 South Carolina 7, Georgia Southern 4 | J.Kucharski (W, 4-0) | B.Kish (4) | Columbia, SC | | P.Hollins, J.Curl, K.Taylor |
| 04/26 | South Carolina 8, Georgia Southern 1 | B.Landrum (W) | | Columbia, SC | | R.Carraway |
| 04/28 | South Carolina 6, Mercer 3 | B.Baynham (W, 4-2) | | Macon, GA | | |
| 04/29 | South Carolina 6, Wingate 3 | M.Calvert (W, 5-0) | M.Small (3) | Columbia, SC | | |
| 04/30 | South Carolina 6, Erskine 5 | B.Kish (W) | | Columbia, SC | | |
| 05/01 | Citadel 8, South Carolina 6 | J.Kucharski (L, 1-1) | | Charleston, SC | | |
| 05/03 | #6 South Carolina 10, UNC-Wilmington 4 | B.Baynham (W, 5-2) | B.Kish (6) | Columbia, SC | | J.Thaw, J.Curl |
| 05/10 | South Carolina 6, Clemson 1 | B.Landrum (W, 9-2) | | Columbia, SC | | |
| 05/11 | #2 South Carolina 4, Clemson 1 | D.Lubert (W, 6-1) | B.Kish (7) | Columbia, SC | | |
| 05/22 | South Carolina 7, Georgia Southern 2 | B.Landrum (W, 10-2) | | Clemson, SC | NCAA Atlantic Regional | G.Jonson |
| 05/24 | Clemson 6, South Carolina 2 | D.Lubert (L, 6-2) | | Clemson, SC | NCAA Atlantic Regional | |
| 05/25 | South Carolina 8, East Tennessee State 5 | B.Baynham (W, 6-2) | B.Kish (8) | Clemson, SC | NCAA Atlantic Regional | K.Taylor (4) |
| 05/25 | Clemson 17, South Carolina 12 | J.Kucharski (L, 4-2) | | Clemson, SC | NCAA Atlantic Regional | R.Carraway (5) |