| 1959 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 03/20 | South Carolina 13, Erskine 1 | | | Columbia, SC | | D.Morgan (1) |
| 03/25 | Kentucky 12, South Carolina 7 | R.Brown (L) | | Columbia, SC | | B.Ellenburg |
| 03/26 | South Carolina 2, Kentucky 1 | R.Groves (W) | | Columbia, SC | | |
| 03/27 | Maryland 3, South Carolina 2 | M.Quick (L) | | Columbia, SC | ACC | |
| 03/28 | South Carolina 6, Virginia 1 | B.Swygert (W) | | Columbia, SC | ACC | D.Morgan, K.Rosefield |
| 03/31 | Wake Forest 3, South Carolina 1 | R.Groves (L) | | Columbia, SC | ACC | |
| 04/03 | Clemson 11, South Carolina 0 | E.Newman (L) | | Columbia, SC | ACC | |
| 04/04 | Newberry 5, South Carolina 4 | B.Swygert (L) | | Newberry, SC | | |
| 04/06 | N.C. State 3, South Carolina 2 | R.Brown (L) | | Columbia, SC | ACC | |
| 04/06 | South Carolina 8, N.C. State 0 | M.Quick (W) | | Columbia, SC | ACC | |
| 04/07 | South Carolina 8, North Carolina 3 | R.Groves (W, 2) | | Columbia, SC | ACC | |
| 04/09 | Citadel 6, South Carolina 5 | | | Charleston, SC | | |
| 04/09 | South Carolina 3, Citadel 0 | R.Brown (W) | | Charleston, SC | | |
| 04/14 | Virginia 1, South Carolina 0 | R.Groves (L) | | Charlottesville, VA | ACC | |
| 04/17 | South Carolina 8, Duke 4 | R.Brown (W) | | Columbia, SC | ACC | |
| 04/20 | South Carolina 9, Georgia Southern 6 | M.Quick (W) | | Columbia, SC | | B.Shore |
| 04/21 | South Carolina 7, Georgia Southern 5 | C.Jones (W) | | Columbia, SC | | |
| 04/24 | Wake Forest 1, South Carolina 0 | R.Groves (L) | | Winston Salem, NC | ACC | |
| 04/25 | North Carolina 4, South Carolina 1 | R.Brown (L) | | Chapel Hill, NC | ACC | |
| 05/02 | South Carolina 8, Duke 3 | R.Groves (W) | | Durham, NC | ACC | K.Rosefield, J.Roof |
| 05/04 | Erskine 4, South Carolina 1 | R.Brown (L) | | Columbia, SC | | |
| 05/04 | South Carolina 7, Erskine 2 | E.Newman (W) | | Columbia, SC | | |
| 05/05 | South Carolina 7, Newberry 5 | | | Columbia, SC | | |
| 05/08 | Clemson 10, South Carolina 1 | R.Groves (L) | | Clemson, SC | ACC | |