| 1978 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 02/27 | Baptist 8, South Carolina 6 | H.Hutchens (L, 0-1) | | Charleston, SC | | |
| 03/01 | South Carolina 24, Elon 2 | J.Twitty (W, 1-0) | | Columbia, SC | | J.Marquardt, J.Long, R.Rodgers |
| 03/02 | South Carolina 4, Coastal Carolina 3 | H.Gaalema (W, 1-0) | | Columbia, SC | | |
| 03/04 | South Carolina 6, Campbell 1 | B.Landrum (W, 1-0) | | Columbia, SC | | R.Crapps (1) |
| 03/04 | Campbell 5, South Carolina 4 | H.Gaalema (L, 1-1) | | Columbia, SC | | C.McLean (1) |
| 03/06 | South Carolina 11, James Madison 3 | J.Twitty (W, 2-0) | | Columbia, SC | | J.Marquardt, R.Crapps |
| 03/07 | South Carolina 4, East Carolina 3 | A.Scott (W, 1-0) | | Columbia, SC | | |
| 03/11 | Virginia 4, South Carolina 1 | J.Twitty (L, 2-1) | | Columbia, SC | | |
| 03/12 | South Carolina 13, Virginia 3 | B.Landrum (W, 2-0) | | Columbia, SC | | C.McLean 2 |
| 03/13 | South Carolina 5, George Mason 0 | M.Kish (W, 1-0) | | Columbia, SC | | J.Maquardt, C.McLean |
| 03/14 | Jacksonville 6, South Carolina 3 | A.Scott (L, 1-1) | | Jacksonville, FL | | |
| 03/15 | South Carolina 3, Jacksonville 1 | H.Hutchens (W) | | Jacksonville, FL | | |
| 03/18 | South Carolina 5, Mercer 3 | J.Chakales (W, 1-0) | H.Gaalema | Macon, GA | | J.Marquardt |
| 03/19 | North Carolina 4, South Carolina 3 | J.Twitty (L, 2-2) | | Columbia, SC | | |
| 03/20 | South Carolina 8, SIU-Edwardsville 0 | A.Scott (W, 2-1) | | Columbia, SC | | E.Adams |
| 03/21 | South Carolina 3, SIU-Edwardsville 2 | M.Toalson (W,1) | | Columbia, SC | | |
| 03/24 | South Carolina 13, Lenoir-Rhyne 1 | B.Landrum (W, 3-0) | | Columbia, SC | | |
| 03/25 | South Carolina 13, Lenoir-Rhyne 2 | | | Columbia, SC | | |
| 03/27 | South Carolina 3, Stetson 2 | A.Scott (W, 3-1) | M.Toalson | Columbia, SC | | J.Marquardt |
| 03/28 | South Carolina 12, Western Carolina 9 | M.Toalson (W, 2-0) | | Columbia, SC | | J.Marquardt |
| 03/30 | South Carolina 14, Baptist 2 | B.Baynham (W, 1-0) | | Columbia, SC | | J.Marquardt 2 |
| 04/01 | Clemson 10, South Carolina 2 | J.Twitty (L, 3-3) | | Columbia, SC | | J.Long |
| 04/02 | South Carolina 10, Clemson 6 | A.Scott (W, 4-1) | | Columbia, SC | | W.Westbrook 2 (3), E.Adams (1) |
| 04/04 | South Carolina 7, Newberry 3 | B.Landrum (W, 4-0) | | Newberry, SC | | P.Hollins |
| 04/06 | South Carolina 12, Furman 2 | J.Twitty (W, 4-3) | | Greenville, SC | | |
| 04/07 | South Carolina 7, Pfeiffer 6 | | | Columbia, SC | | |
| 04/08 | Mercer 9, South Carolina 8 | M.Toalson (L, 2-1) | | Columbia, SC | | J.Marquardt |
| 04/10 | Georgia Southern 2, South Carolina 1 | B.Landrum (L, 4-1) | | Columbia, SC | | J.Marquardt |
| 04/11 | South Carolina 7, Georgia Southern 3 | J.Twitty (W, 5-3) | | Columbia, SC | | E.Adams |
| 04/14 | South Carolina 11, North Carolina 3 | A.Scott (W, 5-1) | | Chapel Hill, NC | | |
| 04/15 | North Carolina 4, South Carolina 0 | B.Landrum (L, 4-2) | | Chapel Hill, NC | | |
| 04/16 | East Carolina 9, South Carolina 7 | J.Twitty (L, 5-4) | | Greenville, NC | | |
| 04/18 | South Carolina 7, Citadel 1 | A.Scott (W, 6-1) | | Columbia, SC | | W.Westbrook, P.Hollins |
| 04/19 | Western Carolina 13, South Carolina 6 | H.Gaalema (L, 1-2) | | Asheville, NC | | J.Marquardt (15) |
| 04/20 | South Carolina 7, Furman 0 | B.Landrum (W, 5-2) | | Columbia, SC | | |
| 04/21 | South Carolina 15, Wofford 4 | B.Baynham (W, 2-0) | | Columbia, SC | | J.Marquardt, C.MacLean, G.Jonson, R.Crapps |
| 04/22 | South Carolina 14, Tennessee 4 | A.Scott (W, 7-1) | | Knoxville, TN | | J.Long |
| 04/23 | South Carolina 11, Tennessee 6 | J.Twitty (W, 6-4) | | Knoxville, TN | | W.Westbrook, E.Adams |
| 04/26 | Citadel 3, South Carolina 2 | A.Scott (L, 7-2) | | Charleston, SC | | |
| 04/28 | South Carolina 6, Georgia Tech 3 | B.Landrum (W, 6-2) | | Columbia, SC | | E.Adams |
| 04/29 | #11 South Carolina 9, Georgia Tech 3 | M.Kish (W, 3-0) | | Columbia, SC | | J.Long |
| 04/30 | Clemson 11, South Carolina 4 | A.Scott (L, 7-3) | | Clemson, SC | | |
| 05/02 | South Carolina 6, Erskine 0 | B.Landrum (W, 7-2) | | Columbia, SC | | C.McLean (8) |
| 05/14 | South Carolina 5, Virginia Tech 4 | B.Landrum (W, 8-2) | | Blacksburg, VA | | W.Westbrook |
| 05/14 | Virginia Tech 3, South Carolina 0 | A.Scott (L, 7-4) | | Blacksburg, VA | | |