| 1981 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 02/27 | South Carolina 12, Baptist 1 | B.Baynham (W, 1-0) | | Charleston, SC | | P.Hollins (1) |
| 02/28 | South Carolina 2, Pembroke State 0 | M.Calvert (W, 1-0) | | Columbia, SC | | |
| 03/01 | Georgia State 11, South Carolina 3 | J.Kucharski (L, 0-1) | | Atlanta, GA | | R.Lowery (1), R.Lee (1) |
| 03/02 | Georgia State 11, South Carolina 10 | J.Babel (L, 0-1) | | Atlanta, GA | | |
| 03/05 | South Carolina 19, Furman 6 | D.Gordon (W, 1-0) | | Greenville, SC | | R.Lee (2), J.Thaw (1) |
| 03/06 | South Carolina 13, Alderson Broadus 0 | M.Calvert (W, 2-0) | | Columbia, SC | | H.Heise (1), J.Curl (1), A.Finley (1) |
| 03/07 | North Carolina 8, South Carolina 6 | B.Kish (L, 0-1) | | Columbia, SC | | C.Boyle (1), P.Hollins (2) |
| 03/08 | South Carolina 11, North Carolina 4 | J.Kucharski (W, 1-1) | | Columbia, SC | | |
| 03/11 | South Carolina 24, Erskine 2 | B.Baynham (W, 2-0) | | Due West, SC | | J.McCarthy (1) |
| 03/12 | South Carolina 13, Howard 8 | E.Leopard (W, 1-0) | | Columbia, SC | | J.Curl (2), R.Carraway (1), J.Thaw (2) |
| 03/13 | South Carolina 12, Howard 0 | D.Lubert (W, 1-0) | | Columbia, SC | | J.Curl (3), P.Hollins (3), J.Sullivan (1), R.Lowery (2) |
| 03/14 | South Carolina 18, Old Dominion 7 | J.Kucharski (W, 2-1) | | Columbia, SC | | P.Hollins 2(5), C.Boyle (2), J.McCarthy (2) |
| 03/15 | South Carolina 4, Austin Peay 0 | D.Gordon (W, 2-0) | | Columbia, SC | | |
| 03/16 | South Carolina 19, Virginia 7 | B.Baynham (W, 3-0) | | Columbia, SC | | C.Boyle (3), R.Lowery 2(4), J.Curl (4) |
| 03/17 | South Carolina 3, Virginia 2 | D.Lubert (W, 2-0) | | Columbia, SC | | R.Lowery (5), J.Curl (5) |
| 03/20 | Florida State 9, South Carolina 8 | J.Kucharski (L, 1-2) | | Tallahassee, FL | | R.Vollmer (1) |
| 03/21 | South Carolina 8, Florida State 5 | B.Baynham (W, 4-0) | | Tallahassee, FL | | C.Boyle (4) |
| 03/22 | Florida State 12, South Carolina 6 | D.Lubert (L, 2-1) | | Tallahassee, FL | | |
| 03/23 | South Carolina 19, Georgia Southwestern 13 | E.Leopard (W, 2-0) | | Americus, GA | | |
| 03/25 | South Carolina 9, Mercer 6 | D.Gordon (W, 3-0) | | Macon, GA | | |
| 03/26 | South Carolina 13, Mercer 2 | B.Baynham (W, 5-0) | | Macon, GA | | J.Thaw (3), J.McCarthy (3) |
| 03/27 | South Carolina 9, Ohio State 1 | D.Lubert (W, 3-1) | | Columbia, SC | | C.Boyle (5), J.Thaw (4), J.Curl (8) |
| 03/28 | Ohio State 12, South Carolina 6 | M.Calvert (L, 2-1) | | Columbia, SC | | J.Curl (8) |
| 03/29 | South Carolina 4, Ohio 2 | J.Kucharski (W, 2-2) | | Columbia, SC | | |
| 03/30 | South Carolina 5, Ohio 0 | D.Gordon (W, 4-0) | | Columbia, SC | | |
| 03/31 | South Carolina 9, Stetson 2 | B.Baynham (W, 6-0) | | Columbia, SC | | R.Carraway (4), R.Lowery (6), P.Hollins (6) |
| 04/01 | South Carolina 8, Citadel 6 | E.Leopard (W, 3-0) | | Columbia, SC | | P.Hollins (7), R.Lowery (7), R.Carraway (5) |
| 04/03 | South Carolina 6, Clemson 2 | D.Lubert (W, 4-1) | | Columbia, SC | | |
| 04/04 | #18 South Carolina 12, Clemson 7 | J.Babel (W, 1-1) | | Columbia, SC | | |
| 04/06 | South Carolina 5, Winthrop 4 | B.Kish (W, 1-1) | | Rock Hill, SC | | |
| 04/07 | Francis Marion 10, South Carolina 6 | E.Leopard (L, 3-1) | | Columbia, SC | | |
| 04/08 | South Carolina 7, Tennessee 4 | D.Lubert (W, 5-1) | | Knoxville, TN | | R.Carrawy (6), J.Curl (9) |
| 04/10 | #16 South Carolina 8, Newberry 0 | D.Gordon (W, 5-0) | | Columbia, SC | | C.Boyle (6) |
| 04/13 | Clemson 5, South Carolina 4 | B.Kish (L, 1-2) | | Clemson, SC | | |
| 04/14 | South Carolina 12, Clemson 2 | D.Lubert (W, 6-1) | | Clemson, SC | | J.Curl (10) |
| 04/17 | Florida State 7, South Carolina 5 | D.Gordon (L, 5-1) | | Columbia, SC | | |
| 04/19 | South Carolina 9, Florida State 3 | D.Lubert (W, 7-1) | | Columbia, SC | | |
| 04/21 | South Carolina 5, Mercer 0 | B.Baynham (W, 7-0) | | Columbia, SC | | |
| 04/22 | South Carolina 7, Citadel 4 | D.Gordon (W, 6-1) | | Charleston, SC | | |
| 04/23 | #17 South Carolina 10, Baptist 3 | J.Kucharski (W, 3-2) | | Columbia, SC | | C.Boyle (7), P.Hollins (8) |
| 04/24 | #17 South Carolina 13, #18 Georgia Southern 5 | D.Lubert (W, 8-1) | | Columbia, SC | | P.Hollins 2(10) |
| 04/25 | South Carolina 7, Georgia Southern 6 | J.Babel (W, 2-1) | | Columbia, SC | | |
| 04/26 | South Carolina 12, Pfeiffer 11 | J.Babel (W, 3-1) | | Columbia, SC | | R.Carraway (7) |
| 04/27 | UNC-Wilmington 5, South Carolina 1 | D.Gordon (L, 6-2) | | Wilmington, NC | | |
| 04/28 | North Carolina 4, South Carolina 3 | J.Babel (L, 3-2) | | Chapel Hill, NC | | |
| 04/29 | South Carolina 10, North Carolina 1 | D.Lubert (W, 9-1) | | Chapel Hill, NC | | |
| 05/02 | South Carolina 10, Furman 6 | B.Baynham (W, 7-0) | | Columbia, SC | | J.Curl (11) |
| 05/04 | South Carolina 8, Wingate 2 | D.Gordon (W, 7-2) | | Columbia, SC | | J.McCarthy (4), C.Boyle (8), J.Thaw 2(6) |
| 05/06 | South Carolina 7, Georgia Southern 3 | D.Lubert (W, 10-1) | | Allendale, SC | | J.McCarthy (5), J.Curl (12) |
| 05/16 | South Carolina 5, Georgia State 2 | D.Lubert (W, 11-1) | | Columbia, SC | | P.Hollins 2(12), J.Curl (13) |
| 05/16 | Georgia State 3, South Carolina 2 | D.Gordon (L, 7-3) | | Columbia, SC | | |
| 05/17 | Georgia Southern 6, South Carolina 0 | B.Baynham (L, 7-1) | | Statesboro, GA | | |
| 05/18 | South Carolina 6, Georgia Southern 1 | J.Kucharski (W, 4-2) | | Statesboro, GA | | P.Hollins 2(14) |
| 05/22 | South Carolina 15, Temple 6 | D.Lubert (W, 12-1) | B.Kish | Columbia, SC | NCAA Atlantic Regional | J.Curl 2(15), R.Lowery (8), J.Thaw (7) |
| 05/23 | South Carolina 8, Memphis 5 | B.Baynham (W, 8-1) | B.Kish | Columbia, SC | NCAA Atlantic Regional | R.Vollmer (2), R.Lowery (9), R.Carraway (8) |
| 05/24 | South Carolina 11, Memphis 5 | D.Gordon (W, 8-3) | | Columbia, SC | NCAA Atlantic Regional | C.Boyle (9), R.Vollmer (3), R.Lowery (10), J.Thaw (8) |
| 05/31 | Oklahoma State 8, South Carolina 5 | B.Kish (L, 1-3) | | Omaha, NE | College World Series | |
| 06/02 | South Carolina 12, Maine 7 | J.Kucharski (W, 5-2) | | Omaha, NE | College World Series | R.Lowery 2(12), J.Curl (16) |
| 06/04 | South Carolina 6, Mississippi State 5 | B.Baynham (W, 9-1) | | Omaha, NE | College World Series | R.Lowery (13), C.Boyle (10) |
| 06/06 | Arizona State 10, South Carolina 7 | D.Lubert (L, 12-2) | | Omaha, NE | College World Series | J.Curl (17) |