| 2000 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 02/04 | South Carolina 13, Charleston Southern 5 | K.Bouknight (W, 1-0) | | Columbia, SC | | S.Nelson (1), C.Plummer (1), B.Pack 2(2) |
| 02/05 | South Carolina 10, Charleston Southern 2 | P.Bauer (W, 1-0) | | Columbia, SC | | B.Dees (1), T.Kelly (1) |
| 02/11 | South Carolina 3, Old Dominion 1 | K.Bouknight (W, 2-0) | L.Gronkiewicz (1) | Charleston, SC | | |
| 02/12 | South Carolina 12, East Carolina 1 | S.Barber (W, 1-0) | | Charleston, SC | | T.Kelly (2), D.Meyer (1) |
| 02/13 | South Carolina 4, Citadel 2 | L.Gronkewicz (W, 1-0) | | Charleston, SC | | T.Kelly (3) |
| 02/18 | South Carolina 19, Delaware State 0 | K.Bouknight (W, 3-0) | | Columbia, SC | | M.Riddle (1), T.Kelly 2(5) |
| 02/19 | South Carolina 16, Delaware State 1 | E.Bascuas (W, 1-0) | | Columbia, SC | | C.Plummer (2), N.Janowicz (1), M.McBeth (1) |
| 02/20 | South Carolina 9, Delaware State 1 | B.Price (W, 1-0) | | Columbia, SC | | D.Meyer (2), T.Kelly (6) |
| 02/22 | South Carolina 10, Campbell 2 | S.Barber (W, 2-0) | | Columbia, SC | | B.Pack (3), M.McBeth (2) |
| 02/25 | South Carolina 4, College of Charleston 0 | K.Bouknight (W, 4-0) | | Columbia, SC | | N.Janowicz (2) |
| 02/26 | South Carolina 5, College of Charleston 2 | P.Bauer (W, 2-0) | S.Barber (1) | Columbia, SC | | N.Janowicz (3), B.Mobley (1) |
| 02/27 | South Carolina 10, College of Charleston 3 | J.Poston (W, 1-0) | | Columbia, SC | | |
| 03/03 | South Carolina 8, Radford 4 | K.Bouknight (W, 5-0) | | Columbia, SC | | B.Dees 2(3), B.Mobley (2), T.Kelly (7), J.McHenry (1) |
| 03/04 | South Carolina 7, Radford 4 | P.Bauer (W, 3-0) | | Columbia, SC | | |
| 03/05 | South Carolina 13, Radford 1 | S.Barber (W, 3-0) | | Columbia, SC | | D.Meyer (3), B.Pack (4), T.Dyson (1) |
| 03/08 | South Carolina 13, Furman 2 | B.Price (W, 2-0) | | Columbia, SC | | N.Janowicz (4), B.Dees (4), B.Pack (5), B.Jeffcoat (1), T.Kelly (8) |
| 03/10 | South Carolina 12, Auburn 6 | K.Bouknight (W, 6-0) | S.Barber (2) | Auburn, AL | SEC | D.Meyer (4), B.Pack (6), S.Nelson (2), J.McHenry (2) |
| 03/11 | South Carolina 10, Auburn 9 | E.Bascuas (W, 2-0) | S.Barber (3) | Auburn, AL | SEC | C.Plummer (3), T.Kelly (9), M.McBeth (3) |
| 03/12 | South Carolina 8, Auburn 7 | C.Collins (W, 1-0) | | Auburn, AL | SEC | J.McHenry (3) |
| 03/14 | South Carolina 3, UNC-Asheville 1 | J.Poston (W, 2-0) | S.Barber (4) | Columbia, SC | | |
| 03/17 | South Carolina 5, Florida 2 | K.Bouknight (W, 7-0) | S.Barber (5) | Columbia, SC | SEC | |
| 03/18 | South Carolina 7, Florida 3 | P.Bauer (W, 4-0) | | Columbia, SC | SEC | |
| 03/19 | Florida 17, South Carolina 8 | C.Collins (L, 1-1) | | Columbia, SC | SEC | D.Meyer (5), B.Pack (7) |
| 03/22 | South Carolina 17, Wofford 2 | B.Price (W, 3-0) | | Columbia, SC | | B.Dees (5) |
| 03/24 | LSU 8, South Carolina 6 | S.Barber (L, 3-1) | | Baton Rouge, LA | SEC | T.Kelly (10) |
| 03/25 | LSU 7, South Carolina 6 | J.Wesley (L, 0-1) | | Baton Rouge, LA | SEC | B.Pack (8), M.McBeth (4) |
| 03/26 | South Carolina 9, LSU 7 | J.Poston (W, 3-0) | J.Wesley (1) | Baton Rouge, LA | SEC | B.Pack (9), T.Dyson (2) |
| 03/28 | South Carolina 4, College of Charleston 1 | M.Wilson (W, 1-0) | S.Barber (6) | Columbia, SC | | M.McBeth (5) |
| 03/29 | Elon 7, South Carolina 5 | S.Whetstone (L, 0-1) | | Columbia, SC | | |
| 03/31 | South Carolina 4, Alabama 1 | K.Bouknight (W, 8-0) | | Columbia, SC | SEC | D.Meyer (6), T.Kelly (11) |
| 04/01 | South Carolina 2, Alabama 0 | P.Bauer (W, 5-0) | | Columbia, SC | SEC | |
| 04/02 | South Carolina 3, Alabama 1 | S.Barber (W, 4-1) | J.Wesley (2) | Columbia, SC | SEC | |
| 04/05 | South Carolina 6, Citadel 5 | J.Wesley (W, 1-1) | | Columbia, SC | | B.Dees (6) |
| 04/07 | South Carolina 1, Mississippi State 0 | K.Bouknight (W, 9-0) | | Columbia, SC | SEC | |
| 04/08 | South Carolina 4, Mississippi State 3 | P.Bauer (W, 6-0) | S.Barber (7) | Columbia, SC | SEC | |
| 04/09 | South Carolina 7, Mississippi State 6 | C.Collins (W, 2-1) | | Columbia, SC | SEC | B.Pack (10), T.Dyson (3) |
| 04/12 | South Carolina 6, Clemson 3 | K.Bouknight (W, 10-0) | S.Barber (8) | Clemson, SC | | D.Meyer (7), B.Pack (11) |
| 04/14 | South Carolina 14, Vanderbilt 5 | P.Bauer (W, 7-0) | | Nashville, TN | SEC | |
| 04/15 | South Carolina 2, Vanderbilt 1 | S.Barber (W, 5-1) | | Nashville, TN | SEC | |
| 04/16 | South Carolina 7, Vanderbilt 3 | K.Bouknight (W, 11-0) | | Nashville, TN | SEC | |
| 04/18 | South Carolina 15, Davidson 0 | C.Spigner (W, 1-0) | | Columbia, SC | | T.Dyson (4), T.Kelly (12) |
| 04/19 | South Carolina 9, Clemson 8 | S.Barber (W, 6-1) | | Columbia, SC | | D.Meyer (8), T.Dyson (5), C.Plummer (4) |
| 04/22 | South Carolina 15, Kentucky 5 | K.Bouknight (W, 12-0) | S.Barber (9) | Lexington, KY | SEC | N.Janowicz (5), B.Pack 2(13), T.Dyson (6), T.Kelly (13), C.Plummer (5) |
| 04/22 | South Carolina 11, Kentucky 10 | J.Wesley (W, 2-1) | S.Barber (10) | Lexington, KY | SEC | B.Pack, T.Dyson, M.McBeth |
| 04/23 | South Carolina 18, Kentucky 6 | P.Bauer (W, 6-0) | | Lexington, KY | SEC | T.Dyson (9), T.Kelly (16) |
| 04/26 | South Carolina 7, UNC-Asheville 3 | C.Spigner (W, 2-0) | | Asheville, NC | | B.Dees (7), C.Plummer (6) |
| 04/28 | South Carolina 9, Georgia 5 | K.Bouknight (W, 13-0) | S.Barber (11) | Columbia, SC | SEC | T.Dyson (9), T.Kelly (16), M.McBeth (8) |
| 04/29 | South Carolina 7, Georgia 5 | P.Bauer (W, 9-0) | S.Barber (12) | Columbia, SC | SEC | T.Kelly (17) |
| 04/30 | South Carolina 9, Georgia 7 | C.Collins (W, 3-1) | | Columbia, SC | SEC | B.Pack (15) |
| 05/05 | South Carolina 8, Arkansas 2 | K.Bouknight (W, 14-0) | | Fayetteville, AR | SEC | B.Dees (8) |
| 05/06 | Arkansas 11, South Carolina 10 | P.Bauer (L, 9-1) | | Fayetteville, AR | SEC | |
| 05/07 | Arkansas 9, South Carolina 3 | B.Price (L, 3-1) | | Fayetteville, AR | SEC | |
| 05/09 | South Carolina 10, Duke 9 | P.Bauer (W, 10-1) | | Durham, NC | | T.Dyson (10), T.Kelly (18) |
| 05/12 | South Carolina 14, Tennessee 3 | K.Bouknight (W, 15-0) | | Columbia, SC | SEC | T.Dyson (11) |
| 05/13 | South Carolina 9, Tennessee 1 | P.Bauer (W, 11-1) | | Columbia, SC | SEC | B.Dees (9) |
| 05/14 | South Carolina 11, Tennessee 7 | S.Barber (W, 7-1) | J.Wesley (3) | Columbia, SC | SEC | A.Rios (1), C.Plummer (7) |
| 05/17 | Kentucky 6, South Carolina 4 | K.Bouknight (L, 15-1) | | Hoover, AL | SEC Tournament | |
| 05/18 | South Carolina 11, Auburn 4 | P.Bauer (W, 12-1) | S.Barber (13) | Hoover, AL | SEC Tournament | C.Plummer (8) |
| 05/19 | South Carolina 12, Kentucky 5 | S.Barber (W, 8-1) | | Hoover, AL | SEC Tournament | T.Kelly |
| 05/20 | Florida 12, South Carolina 4 | S.Whetstone (L, 0-2) | | Hoover, AL | SEC Tournament | D.Meyer (9) |
| 05/26 | South Carolina 6, Liberty 4 | K.Bouknight (W, 16-1) | S.Barber (14) | Columbia, SC | NCAA Regional | C.Plummer (9) |
| 05/27 | South Carolina 6, Wake Forest 1 | P.Bauer (W, 13-1) | | Columbia, SC | NCAA Regional | D.Meyer (10), B.Dees (10), T.Kelly (20) |
| 05/28 | South Carolina 8, Wake Forest 4 | S.Barber (W, 9-1) | | Columbia, SC | NCAA Regional | B.Pack (16), A.Rios (2), M.McBeth (9) |
| 06/02 | South Carolina 6, Louisiana-Lafayette 3 | K.Bouknight (W, 17-1) | S.Barber (15) | Columbia, SC | NCAA Super Regional | D.Meyer (11), T.Kelly (21) |
| 06/03 | Louisiana-Lafayette 7, South Carolina 1 | P.Bauer (L, 13-2) | | Columbia, SC | NCAA Super Regional | |
| 06/04 | Louisiana-Lafayette 3, South Carolina 2 | S.Barber (L, 9-2) | | Columbia, SC | NCAA Super Regional | T.Kelly (22) |