| 2005 Results | | Date | Result | SC W/L | SC Save | Location | Game Type | SC HR |
| 02/11 | South Carolina 5, Longwood 1 | A.Rawl (W, 1-0) | | Columbia, SC | | I.Paxton |
| 02/12 | South Carolina 4, Longwood 1 | Z.McCamie (W, 1-0) | B.Marsh (1) | Columbia, SC | | Mi.Campbell (1) |
| 02/13 | South Carolina 13, Longwood 3 | W.Pelzer (W, 1-0) | | Columbia, SC | | B.Winn |
| 02/18 | #7 South Carolina 20, Radford 0 | A.Rawl (W, 2-0) | | Columbia, SC | | J.Willard (1) |
| 02/19 | #7 South Carolina 16, Radford 4 | Z.McCamie (W, 2-0) | | Columbia, SC | | C.Vanderhook (1), R.Mahoney (1) |
| 02/20 | #7 South Carolina 7, Radford 4 | A.Cruse (W, 1-0) | C.Lalor (1) | Columbia, SC | | S.Tolleson (1), B.Winn 2(3) |
| 02/25 | #5 South Carolina 8, Niagra 3 | A.Rawl (W, 3-0) | B.Marsh (2) | Columbia, SC | | N.Gielser (1) |
| 02/26 | #5 South Carolina 19, Niagra 1 | Z.McCamie (W, 3-0) | | Columbia, SC | | S.Pearce 2(2), J.Willard (2), P.Disher (1), B.Winn 2(5) |
| 02/27 | #5 South Carolina 6, Niagra 2 | J.Fletcher (W, 1-0) | | Columbia, SC | | S.Pearce (3), J.Willard (3) |
| 03/02 | #5 South Carolina 13, Wofford 1 | A.Lambert (W, 1-0) | | Columbia, SC | | M.Campbell (2), B.Winn (6) |
| 03/04 | Pepperdine 7, #5 South Carolina 5 | A.Rawl (L, 3-1) | | Minneapolis, MN | | |
| 03/05 | #5 South Carolina 13, Minnesota 6 | Z.McCamie (W, 4-0) | | Minneapolis, MN | | T.King (1), M.Campbell (3) |
| 03/06 | #5 South Carolina 9, New Orleans 3 | J.Fletcher (W, 2-0) | | Minneapolis, MN | | B.Winn (7) |
| 03/09 | #4 South Carolina 1, Charleston Southern 0 | A.Cruse (W, 2-0) | B.Marsh (3) | Columbia, SC | | |
| 03/12 | #4 South Carolina 6, Clemson 3 | A.Rawl (W, 4-1) | J.Fletcher (1) | Clemson, SC | | C.Brown (1), B.Winn (8) |
| 03/13 | #4 South Carolina 6, Clemson 5 | A.Cruse (W, 3-0) | B.Marsh (4) | Clemson, SC | | S.Pearce (4) |
| 03/15 | #4 South Carolina 6, Wofford 2 | C.Lalor (W, 1-0) | | Spartanburg, SC | | |
| 03/18 | #7 Arkansas 9, #2 South Carolina 1 | A.Rawl (L, 4-2) | | Columbia, SC | SEC | J.Willard (4) |
| 03/19 | #2 South Carolina 12, #7 Arkansas 3 | Z.McCamie (W, 5-0) | | Columbia, SC | SEC | S.Tolleson (2), C.Brown (2), S.Pearce (5) |
| 03/20 | #7 Arkansas 5, #2 South Carolina 3 | W.Pelzer (L, 1-1) | | Columbia, SC | SEC | |
| 03/23 | #6 South Carolina 10, Davidson 1 | A.Lambert (W, 2-0) | | Columbia, SC | | C.Brown (3) |
| 03/25 | #6 South Carolina 2, #11 Florida 0 | A.Rawl (W, 5-2) | J.Fletcher (2) | Gainesville, FL | SEC | |
| 03/26 | #11 Florida 7, #6 South Carolina 3 | Z.McCamie (L, 5-1) | | Gainesville, FL | SEC | |
| 03/27 | #11 Florida 6, #6 South Carolina 1 | J.Fletcher (L, 2-1) | | Gainesville, FL | SEC | |
| 03/29 | #8 South Carolina 7, Brown 2 | B.Marsh (W, 1-0) | | Columbia, SC | | S.Pearce (6) |
| 03/30 | #8 South Carolina 4, Citadel 2 | C.Donald (W, 1-0) | B.Marsh (5) | Charleston, SC | | J.Willard (5) |
| 04/01 | #8 South Carolina 7, Georgia 5 | J.Fletcher (W, 3-1) | | Columbia, SC | SEC | |
| 04/02 | #8 South Carolina 17, Georgia 2 | Z.McCamie (W, 6-1) | | Columbia, SC | SEC | C.Brown (4), S.Pearce (7), D.Gregg (1) |
| 04/03 | #8 South Carolina 6, Georgia 1 | J.Jeffords (W, 1-0) | A.Cruse (1) | Columbia, SC | SEC | S.Pearce (8) |
| 04/06 | #4 South Carolina 9, Citadel 4 | A.Lambert (W, 3-0) | | Columbia, SC | | M.Campbell (4), J.Willard (6) |
| 04/08 | #4 South Carolina 3, #6 LSU 1 | J.Fletcher (W, 4-1) | B.Marsh (6) | Baton Rouge, LA | SEC | |
| 04/09 | #4 South Carolina 5, #6 LSU 1 | Z.McCamie (W, 7-1) | | Baton Rouge, LA | SEC | S.Pearce (9) |
| 04/10 | #4 South Carolina 7, #6 LSU 5 | A.Rawl (W, 6-2) | B.Marsh (7) | Baton Rouge, LA | SEC | M.Campbell 2(6), I.Paxton(2) |
| 04/13 | Clemson 12, #4 South Carolina 2 | A.Cruse (L, 3-1) | | Clemson, SC | | R.Mahoney (2) |
| 04/15 | Vanderbilt 11, #4 South Carolina 3 | J.Fletcher (L, 4-2) | | Columbia, SC | SEC | B.Winn (9) |
| 04/16 | Vanderbilt 2, #4 South Carolina 1 | Z.McCamie (L, 7-2) | | Columbia, SC | SEC | |
| 04/17 | #4 South Carolina 7, Vanderbilt 4 | A.Rawl (W, 7-2) | B.Marsh (8) | Columbia, SC | SEC | S.Tolleson (3) |
| 04/20 | Clemson 7, #8 South Carolina 5 | B.Marsh (L, 1-1) | | Columbia, SC | | |
| 04/22 | #15 Alabama 6, #8 South Carolina 4 | A.Rawl (L, 7-3) | | Tuscaloosa, AL | SEC | S.Pearce (10) |
| 04/23 | #15 Alabama 10, #8 South Carolina 4 | J.Fletcher (L, 4-3) | | Tuscaloosa, AL | SEC | S.Pearce 2(12) |
| 04/24 | #8 South Carolina 5, #15 Alabama 2 | Z.McCamie (W, 8-2) | B.Marsh (9) | Tuscaloosa, AL | SEC | S.Tolleson (4) |
| 04/29 | Auburn 4, #13 South Carolina 1 | A.Rawl (L, 7-4) | | Columbia, SC | SEC | |
| 04/30 | #13 South Carolina 3, Auburn 2 | B.Marsh (W, 2-1) | | Columbia, SC | SEC | |
| 05/01 | #13 South Carolina 8, Auburn 7 | J.Fletcher (W, 5-3) | B.Marsh (10) | Columbia, SC | SEC | P.Disher (2), B.Winn (10), N.Giesler (2) |
| 05/04 | Furman 6, #13 South Carolina 2 | W.Pelzer (L, 1-2) | | Greenville, SC | | B.Winn (11) |
| 05/06 | #13 Tennessee 3, #13 South Carolina 2 | A.Rawl (L, 7-5) | | Knoxville, TN | SEC | S.Tolleson (5) |
| 05/07 | #13 Tennessee 6, #13 South Carolina 5 | B.Marsh (L, 2-2) | | Knoxville, TN | SEC | N.Giesler (2) |
| 05/08 | #13 Tennessee 11, #13 South Carolina 5 | J.Fletcher (L, 5-4) | | Knoxville, TN | SEC | B.Winn (12) |
| 05/10 | #20 South Carolina 12, Wofford 0 | A.Hempy (W, 1-0) | | Columbia, SC | | S.Pearce 2(14) |
| 05/11 | Furman 11, #20 South Carolina 5 | C.Donald (L, 1-1) | | Columbia, SC | | S.Pearce (15) |
| 05/13 | #20 South Carolina 2, #19 Mississippi 0 | A.Rawl (W, 8-5) | | Oxford, MS | SEC | |
| 05/14 | #19 Mississippi 7, #20 South Carolina 2 | Z.McCamie (L, 8-3) | | Oxford, MS | SEC | T.King (2) |
| 05/15 | #19 Mississippi 8, #20 South Carolina 4 | J.Fletcher (L, 5-5) | | Oxford, MS | SEC | S.Pearce (16) |
| 05/20 | #23 South Carolina 9, Kentucky 7 | B.Marsh (W, 3-2) | | Columbia, SC | SEC | N.Giesler (4) |
| 05/21 | #23 South Carolina 12, Kentucky 9 | F.Beverly (W, 1-0) | | Columbia, SC | SEC | Mi.Campbell (7), S.Tolleson (6), S.Pearce (17), N.Giesler (5) |
| 05/22 | #23 South Carolina 12, Kentucky 1 | A.Hempy (W, 2-0) | | Columbia, SC | SEC | S.Pearce (18) |
| 05/25 | #20 South Carolina 12, #8 Tennessee 2 | A.Rawl (W, 9-5) | | Hoover, AL | SEC Tournament | S.Pearce (19) |
| 05/26 | Mississippi State 6, #20 South Carolina 2 | Z.McCamie (L, 8-4) | | Hoover, AL | SEC Tournament | |
| 05/27 | #10 Tennessee 4, #20 South Carolina 1 | B.Marsh (L, 3-3) | | Hoover, AL | SEC Tournament | |
| 06/03 | #20 South Carolina 6, Michigan 5 | B.Marsh (W, 4-3) | | Atlanta, GA | NCAA Regional | |
| 06/04 | #5 Georgia Tech 10, #23 South Carolina 2 | A.Hempy (L, 2-1) | | Atlanta, GA | NCAA Regional | |
| 06/05 | #23 South Carolina 4, Michigan 3 | Z.McCamie (W, 9-4) | B.Marsh (11) | Atlanta, GA | NCAA Regional | N.Giesler (6) |
| 06/05 | #23 South Carolina 8, #5 Georgia Tech 3 | A.Lambert (W, 4-0) | | Atlanta, GA | NCAA Regional | M.Campbell (8), S.Pearce 2(21) |
| 06/06 | #5 Georgia Tech 5, #23 South Carolina 0 | A.Rawl (L, 9-6) | | Atlanta, GA | NCAA Regional | |