GamecockArchives.com
| Games | | Date | Opponent | USC | Opp | City | St | Attendance |
2010-09-02 | Southern Mississippi | 41 | 13 | Columbia | SC | 70438 |
| Passing - Single Game Yards | | Rank | Name | Date | Opponent | Att | Com | Pct | Yds | TD | Int | Rtg |
| 1 | Stephen Garcia | 2010-09-02 | Southern Mississippi | 23 | 16 | 69.6 | 193 | 0 | 0 | 140.05 |
| 2 | Connor Shaw | 2010-09-02 | Southern Mississippi | 5 | 4 | 80.0 | 32 | 1 | 0 | 134.42 |
| 3 | Stephon Gilmore | 2010-09-02 | Southern Mississippi | 1 | 0 | 0.0 | 0 | 0 | 0 | 0.00 |
| 4 | Andrew Clifford | 2010-09-02 | Southern Mississippi | 1 | 0 | 0.0 | 0 | 0 | 1 | -2.00 |
| 5 | | | | | | | | | | |
| Rushing - Single Game Yards | | Rank | Name | Date | Opponent | Att | Yds | Avg | TD |
| 1 | Marcus Lattimore | 2010-09-02 | Southern Mississippi | 14 | 54 | 3.9 | 2 |
| 2 | Ace Sanders | 2010-09-02 | Southern Mississippi | 1 | 53 | 53.0 | 0 |
| 3 | Stephen Garcia | 2010-09-02 | Southern Mississippi | 5 | 38 | 7.6 | 2 |
| 4 | Connor Shaw | 2010-09-02 | Southern Mississippi | 7 | 31 | 4.4 | 0 |
| 5 | Kenny Miles | 2010-09-02 | Southern Mississippi | 4 | 24 | 6.0 | 0 |
| Receiving - Single Game Yardage | | Rank | Name | Date | Opponent | Rec | Yds | Avg | >TD |
| 1 | Alshon Jeffery | 2010-09-02 | Southern Mississippi | 7 | 106 | 15.1 | 0 |
| 2 | Ace Sanders | 2010-09-02 | Southern Mississippi | 2 | 47 | 23.5 | 0 |
| 3 | Marcus Lattimore | 2010-09-02 | Southern Mississippi | 2 | 21 | 10.5 | 0 |
| 4 | Jason Barnes | 2010-09-02 | Southern Mississippi | 1 | 16 | 16.0 | 0 |
| 5 | D.L. Moore | 2010-09-02 | Southern Mississippi | 1 | 15 | 15.0 | 1 |